![]() ![]() This regulates the pH of the plasma and therefore is important in the acid-base balance. Aldosterone also activates the mechanism of hydrogen ion secretion in the collecting ducts. ![]() ![]() This makes it easier for potassium and sodium to pass through. Once bound, distal tubule membrane permeability increases. When working specifically at this location the hormone binds to mineralocorticoid receptors on the membrane of the distal tubule. The main function of aldosterone is to increase reabsorption within the latter portion of the distal tubule of the nephron and the collecting ducts. Its action affects sodium, potassium and water levels via the excretory and circulatory systems. It is part of the renin angiotensin aldosterone system or RAAS and is an integral part of the complex mechanisms that control water and electrolyte balance within the body. Aldosterone (C 21H 28O 5) is a mineralocorticoid hormone compound secreted by the adrenal gland cortex. ![]()
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